Creating Figures: A Basic Recipe for Image Composites Using Photoshop and PowerPoint
Photoshop vs. PowerPoint: Which one should I use?
Photoshop and PowerPoint are both very flexible applications-each is capable of performing raster image manipulation as well as text and vector editing with varying degrees of success, reliability and ease. While Photoshop is the choice for making adjustments to your raster image’s file format, resolution, size, contrast, color balance, alignment and to crop or merge images together (image editing), PowerPoint is preferred for creating figures and doing image compositing and annotation because the text and vector based annotation will remain sharp. This is not the case for these vector-based elements in Photoshop- there is a loss in quality of text and vector objects when changing file formats to non-proprietary, pixel-based formats.
A good rule to follow is use each tool for what it does best:
Use Photoshop for image adjustment, layer-merging, cropping, rotating and editing. Use PowerPoint for annotating with text and lines, editing text and line elements, incorporating tables, graphs, charts and other vectors and creating composites of multiple images.

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